When stem cells grow old: phenotypes and mechanisms of stem cell aging



The molecular effects of caloric restriction. Caloric restriction causes reduced levels of insulin, IGF and amino acids, and increased levels of NAD+ and AMP. These changes are sensed by the insulin-IGF signaling (IIS) pathway, target of…more
https://journals.biologists.com/dev/article/143/1/3/47328/When-stem-cells-grow-old-phenotypes-and-mechanisms

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