Waking up sleeping beauty – persistent IFN-gamma awakens and activates stem cells via BST2

When IFNγ interacts with hematopoietic (blood) stem cells (HSC), it triggers the expression of cell surface molecule BST2. This results in HSC migration away from CAR cells in the bone marrow (left panel)…more Courtesy of the King lab/Cell Reports, 2020.

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